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Thio-TEPA
Thio-TEPA

Item number: TGM-T1250-100mg

Description: Thio-TEPA (Tiofosyl) is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity. Target: DNA Alkylator/Crosslinker, DNA Alkylation, Antibacterial, Antibiotic. Smiles: P(=S)(N1CC1)(N2CC2)N3CC3. References: Gor PP, et al. Breast Y Res. 2010,12(3):R26.
Keywords: Tiofosfamid, Tiofosyl, Triethylenethiophosphoramide
Application: Antineoplastic, Alkylating agent
CAS 52-24-4
MW: 189.22 D
From 31.00€ *
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Thio-TEPA
Thio-TEPA

Item number: Cay23745-250

Thio-TEPA is an alkylating agent with anticancer activity (IC50 = 1.5 µM against P388 murine leukemia cells). It alkylates DNA and inhibits thymidine incorporation (IC50 = 2 µM) inducing irreversible DNA damage. Thio-TEPA crosslinks guanine nucleotides and induces cell cycle arrest via the formation of interstrand...
Keywords: NCI C01649, NSC 6396, Triethylenethiophosphoramide, 1,1',1''-phosphinothioylidynetris-aziridine
Application: Alkylating agent
CAS 52-24-4
MW: 189.2 D
From 67.00€ *
Review