Description: 7ACC1 (D 142) selectively affects a single part of the MCT symporter translocation cycle, leading to strict inhibition of lactate influx. This singular activity is associated with antitumor effects less prone to resistance and side effects. Target: Monocarboxylate transporter. Smiles:...

When compared with AMCA conjugates, conjugates of the UV-light-excitable 7-dialkylaminocoumarin fluorophore have much longer-wavelength excitation and slightly longer-wavelength emission spectra (470 nm).

Solid. Soluble in DMSO or DMF. 7-(Diethylamino)-coumarin-3-carboxylic acid is a reagent for the derivatisation of amines and proteins. It has also been used for labelling synthetic peptides for high-throughput detection.

7-(Diethylamino)coumarin-3-carboxylic acid is a fluorescent probe., It has been used as a FRET acceptor conjugated to neomycin B or tobramycin (Cay-14596) for use in the analysis of bacterial RNA binding. It has also been used as a reactive probe for the derivatization of sulfonamides for laser-induced fluorescent...