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IRAK-1/4 Inhibitor
IRAK-1/4 Inhibitor

Item number: Cay17540-1

Interleukin-1 receptor-associated kinases (IRAKs) are important mediators in the signal transduction of Toll/IL-1 receptor (TIR) family members. Dysregulation of TIR signaling, typified by increased NF-kappaB activity, results in the development of some cancers and other diseases, making the development of IRAK...
Keywords: N-[1-[2-(4-morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitro-benzamide
Application: IRAK1 inhibitor, IRAK4 inhibitor
CAS 509093-47-4
MW: 395.4 D
From 44.00€ *
Review
IRAK-1-4 Inhibitor I
IRAK-1-4 Inhibitor I

Item number: TGM-T2457-100mg

Description: IRAK-1-4 Inhibitor I is a dual inhibitor targeting IRAK1 and IRAK4. Target: IRAK. Smiles: [O-][N+](=O)c1cccc(c1)C(=O)Nc1nc2ccccc2n1CCN1CCOCC1. References: Powers JP, et al. Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg Med Chem Lett. 2006 Jun...
Keywords: IRAK-1/4 Inhibitor I, IRAK-1/4 Inhibitor
Application: IRAK-1-4 inhibitor
CAS 509093-47-4
MW: 395.41 D
From 38.00€ *
Review