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Item number: TGM-T12086-100mg

Description: Mocravimod hydrochloride (KRP-203) is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type 1(S1PR1). Target: LPL Receptor, Others. Smiles: Cl.NC(CO)(CO)CCc1ccc(Sc2cccc(OCc3ccccc3)c2)cc1Cl. References: Potì F, et al. KRP-203, sphingosine 1-phosphate receptor type 1 agonist,...

Keywords:	KRP-203
Application:	Targets sphingosine 1-phosphate receptor 1 (S1PR1, EDG1, CD363)
CAS	509088-69-1
MW:	480.45 D

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KRP 203

Item number: Cay10010426-10

KRP 203 is a sphingosine-1-phosphate receptor 1 (S1P1) agonist. It selectively induces calcium mobilization in CHO-K1 cells expressing mouse S1P1 over mouse S1P3 and S1P4 (EC50s = 0.84, >1,000, and 9.61 nM, respectively). In vivo, KRP 203 (0.3 mg/kg) prevents the development of wasting syndrome, decreases diarrhea...

Keywords:	Mocravimod (hydrochloride), 2-amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol,...
Application:	S1P1 receptor agonist
CAS	509088-69-1
MW:	480.4 D

From 69.00€ *

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