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Ibudilast
Item number: TGM-T2137-100mg
Description: Ibudilast (MN-166)(KC-404,AV-411,MN-166) is a relatively nonselective phosphodiesterase inhibitor. It is approved for use as an anti-inflammatory in Japan. Target: PDE. Smiles: C(C(C)C)(=O)C1=C2N(N=C1C(C)C)C=CC=C2. References: Yamazaki T, et al. Eur J Pharmacol. 2010 Oct 29.
| Keywords: | MN-166, KC-404, AV-411 |
| CAS | 50847-11-5 |
| MW: | 230.31 D |
From 41.00€
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Ibudilast
Item number: Cay14832-25
Ibudilast is an inhibitor of phosphodiesterase 4 (PDE4, IC50s = 54, 65, 239, and 166 nM for PDE4A-D, respectively). It is selective for PDE4 over PDE1, PDE7A, PDE7B, and PDE9A (IC50s = >10,000 nM for all) but does inhibit PDE3A, PDE3B, and PDE5A (IC50s = 1,600, 2,700, and 3,510 nM, respectively). Ibudilast inhibits...
| Keywords: | AV 411, KC-404, 2-methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone |
| Application: | PDE4 inhibitor |
| CAS | 50847-11-5 |
| MW: | 230.3 D |
From 61.00€
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Ibudilast
Item number: AG-CR1-3738-M010
White to off-white solid. Soluble in DMSO (20mg/ml), DMF (20mg/ml) or ethanol (20mg/ml). Chemical. CAS: 50847-11-5. Formula: C14H18N2O. MW: 230.3. Ibudilast is a non-selective PDE (phosphodiesterase) inhibitor found to have anti-inflammatory activity primarily targeting the peripheral immune system and in the CNS...
| Keywords: | AV-411, KC-404, MN166, BRN 0656579, 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone |
| Application: | Non-selective PDE (phosphodiesterase) inhibitor |
| CAS | 50847-11-5 |
| MW: | 230,3 D |
From 33.00€
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