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Item number: Cay30183-5

Vortioxetine is a multimodal serotonergic agent that acts as a serotonin (5-HT, Cay-14332) reuptake inhibitor (Ki = 1.6 nM) and binds to the 5-HT1A, 5-HT1B, 5-HT3A, and 5-HT7 receptors (Kis = 15, 33, 3.7, and 19 nM, respectively). It also binds to the beta1-adrenergic receptor (Ki = 46 nM). It acts as an antagonist...

Keywords:	1-[2-[(2,4-dimethylphenyl)thio]phenyl]-piperazine
Application:	Serotonin receptor antagonist
CAS	508233-74-7
MW:	298.4 D

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Vortioxetine

Item number: LKT-V5870.10

Vortioxetine exhibits neuromodulatory, antidepressant, anxiolytic, and cognition enhancing activities. Vortioxetine modulates serotonin levels in the brain by inhibiting the serotonin transporter (SERT) and 5-HT3A/7 receptors, acting as a partial agonist at the 5-HT1B receptor, and acting as a full agonist at the...

Application:	5-HT3-receptor antagonist, 5-HT7-receptor antagonist, 5-HT1A-receptor agonist
CAS	508233-74-7
MW:	298.45 D

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