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Thalidomide-4-OH
Thalidomide-4-OH

Item number: TGM-T7763-500mg

Description: Thalidomide-4-OH (E3 ligase Ligand 2) (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used to recruit of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) is a linker to form PROTACs. Target: Ligand for E3 Ligase. Smiles: OC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O. References: Marks MG, et...
Keywords: Cereblon ligand 2, E3 ligase Ligand 2
Application: Protac(R) reagent
CAS 5054-59-1
MW: 274.23 D
30.00€ *
Review
E3 Ligase Ligand 2
E3 Ligase Ligand 2

Item number: Cay36664-1

E3 ligase ligand 2 is an active metabolite of thalidomide (Cay-14610) and an intermediate in the synthesis of proteolysis-targeting chimeras (PROTACs) containing thalidomide, a ligand for the E3 ubiquitin ligase cereblon (CRBN), used in targeted protein degradation. E3 ligase ligand 2 is formed from thalidomide via...
Keywords: 4-hydroxy Thalidomide, 2-(2,6-dioxo-3-piperidinyl)-4-hydroxy-1H-isoindole-1,3(2H)-dione
Application: Thalidomide active metabolite, PROTAC synthetic intermediate
CAS 5054-59-1
MW: 274.2 D
From 40.00€ *
Review
4-Hydroxy-thalidomide
4-Hydroxy-thalidomide

Item number: BPS-82001

4-Hydroxy-thalidomide is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTACs.
Application: Protac(R) reagent
CAS 5054-59-1
MW: 274,2 D
810.00€ *
Review