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Item number: TGM-T6276-100mg

Description: NU7441 (KU-57788 (NU7441)) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM). Target: CRISPR/Cas9, DNA-PK. Smiles: O=c1cc(oc2c(cccc12)-c1cccc2c3ccccc3sc12)N1CCOCC1. References: Sunada S, et al. Nontoxic concentration of DNA-PK inhibitor NU7441 radio-sensitizes lung tumor cells with...

Keywords:	NU7441
Application:	DNA-PK inhibitor
CAS	503468-95-9
MW:	413.49 D

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NU 7441

Item number: Cay14881-5

DNA-dependent protein kinase (DNA-PK) catalyzes nonhomologous end-joining, which is required to repair lethal DNA double-strand breaks. Because cells that are defective in DNA double-strand break repair are highly sensitive to ionizing radiation and topoisomerase II poisons, modulating DNA-PK is one strategy to...

Keywords:	Ku-57788, 8-(4-dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one
Application:	DNA-PK inhibitor
CAS	503468-95-9
MW:	413.5 D

From 59.00€ *

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