3 products were found matching "50264-69-2"!
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Lonidamine
Item number: TGM-T0239-100mg
Description: Lonidamine (Diclondazolic Acid) is an indazole carboxylic acid derivative, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK). Target: Mitochondrial Metabolism, Apoptosis, Hexokinase. Smiles: OC(=O)c1nn(Cc2ccc(Cl)cc2Cl)c2ccccc12. References:...
| Keywords: | AF1890, DICA, Diclondazolic Acid |
| CAS | 50264-69-2 |
| MW: | 321.16 D |
From 34.00€
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Lonidamine
Item number: Cay14640-10
Lonidamine, originally identified as a potent antispermatogenic agent, inhibits glycolysis though the inactivation of mitochondria-bound hexokinase. It can decrease oxygen consumption as well as aerobic and anaerobic glycolysis in Ehrlich ascites tumor cells with IC50 values of 90 and 45 µM, respectively. A role for...
| Keywords: | AF 1890, DICA, Diclondazolic Acid, 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid |
| Application: | Anticancer agent, HK1 inhibitor |
| CAS | 50264-69-2 |
| MW: | 321.2 D |
From 67.00€
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Lonidamine
Item number: LKT-L5658.5
A mitochondria-targeting antitumor agent. It has been shown to induce apoptosis in certain cells, and potentiate cisplatin and paclitaxel activity.
| Application: | Anticancer agent |
| CAS | 50264-69-2 |
| MW: | 321,16 D |
From 157.00€
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