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PNU-120596

Item number: TGM-T6950-100mg

Description: PNU-120596 (NSC-216666) is a positive allosteric modulator of alpha7 nAChR with EC50 of 216 nM. Target: AChR. Smiles: COc1cc(OC)c(NC(=O)Nc2cc(C)on2)cc1Cl. References: Hurst RS, et al, J Neurosci, 2005, 25(17), 4396-4405.

Keywords:	NSC 216666
Application:	Positive allosteric CHRNA7 modulator
CAS	501925-31-1
MW:	311.72 D

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PNU 120596

Item number: Cay14304-10

PNU 120596 is a positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor (nAChR), increasing agonist-evoked calcium flux (EC50 = 216 nM). It has no detectable effect on alpha4beta2, alpha3beta4, or alpha9beta10 nAChRs. PNU-120596 increases the frequency of ACh-evoked GABAergic...

Keywords:	NSC 216666, N-(5-chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea
Application:	Positive allosteric CHRNA7 modulator
CAS	501925-31-1
MW:	311.7 D

From 66.00€ *

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