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Odevixibat
Item number: TGM-T16376-100mg
Description: Odevixibat (A4250) is an effective, selective and orally active ileal bile acid transporter inhibitor. Odevixibat has the potential for the treatment of primary biliary cirrhosis. Odevixibat reduces cholestatic liver and bile duct injury in mice model. Target: Others. Smiles:...
| Keywords: | A4250 |
| Application: | Targets solute carrier family 10 (sodium/bile acid cotransporter), member 2 (SLC10A2, ASBT) |
| CAS | 501692-44-0 |
| MW: | 740.93 D |
From 54.00€
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Odevixibat
Item number: Cay35344-1
Odevixibat is an inhibitor of the sodium/bile acid and sulfated solute cotransporter (ASBT, IC50 = 0.16 nM). It inhibits intestinal reabsorption of [75Se]homotaurocholic acid (75SeHCAT) by 74% in ApoE-/- mice when administered at a dose of 0.156 µmol/kg. Formulations containing odevixibat have been used in the...
| Keywords: | A4250,... |
| Application: | ASBT (sodium/bile acid cotransporter) inhibitor |
| CAS | 501692-44-0 |
| MW: | 740.9 D |
From 44.00€
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