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NS 1738
NS 1738

Item number: TGM-T7884-100mg

Description: NS 1738 (NSC-213859) is a positive allosteric modulator of the alpha7-containing neuronal nicotinic acetylcholine receptors (nAChRs). Target: AChR. Smiles: Oc1ccc(Cl)cc1NC(=O)Nc1cc(ccc1Cl)C(F)(F)F. References: Timmermann D B , Gronlien J H , Kohlhaas K L , et al. An Allosteric Modulator of the ?7...
Keywords: NSC 213859
Application: Positive allosteric nAChR (CHRNA7) modulator
CAS 501684-93-1
MW: 365.13 D
From 47.00€ *
Review
NS 1738
NS 1738

Item number: Cay21018-5

NS 1738 is a positive allosteric modulator of the alpha7-containing neuronal nicotinic acetylcholine receptors (nAChRs). When applied in the presence of ACh, NS 1738 increases the peak amplitude of the current flowing through alpha7-containing nAChRs (EC50 = 3.4 µM). NS 1738 displays no substantial activity for...
Keywords: NSC 213859, N-(5-chloro-2-hydroxyphenyl)-N'-[2-chloro-5-(trifluoromethyl)phenyl]-urea
Application: Positive allosteric nAChR (CHRNA7) modulator
CAS 501684-93-1
MW: 365.1 D
From 43.00€ *
Review