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Item number: Cay28714-1

GGTI 2418 is an inhibitor of geranylgeranyl transferase type I (GGTase I, IC50 = 9.5 nM). It is selective for GGTase I over farnysltransferase (FTase, IC50 = 53,000 nM). GGTI 2418 (100 mg/kg) reduces tumor growth in an MDA-MB-231 breast cancer mouse xenograft model.Formal Name:...

Keywords:	N-[[(2S)-4-[(4-methyl-1H-imidazol-5-yl)methyl]-3-oxo-2-(phenylmethyl)-1-piperazinyl]carbonyl]-L-leucine
Application:	GGTase I inhibitor
CAS	501010-06-6
MW:	441.5 D

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