Description: Kojic acid is a fungal metabolite that inhibits tyrosinase, an enzyme involved in melanin synthesis, with an IC50 value of 30.6 µM for mushroom tyrosinase. Target: Parasite, Tyrosinase. Smiles: OCC1=CC(=O)C(O)=CO1. References: Rodrigues A P D , Farias L H S , Carvalho Antonio Sérgio C, et al. A Novel...

Kojic acid is a fungal metabolite that inhibits tyrosinase, an enzyme involved in melanin synthesis, with an IC50 value of 30.6 µM for mushroom tyrosinase. It decreases growth of Leishmania parasites in vitro and in vivo, and it protects mice from damage induced by gamma irradiation. Kojic acid has been used as a...

White solid. Soluble in DMSO, methanol or water. Mycotoxin. Chelation agent with polyfunctional skeleton for development of biologically active compounds, Moderate antibacterial agent, Tyrosinase inhibitor. Inhibits catecholase activity of tyrosinase, Anti-melanogenic. Skin whitening agent, Antioxidant. Reactive...

A naturally occurring chelation agent. Kojic acid may be used on cut fruits to prevent oxidative browning, in seafood to preserve pink and red colors, and in cosmetics to lighten skin. As an example of the latter, it is used to treat skin diseases like melasm. Synonyms: 5-Hydroxy-2-hydroxymethyl-4H-pyran-4-one,...