6 products were found matching "50-76-0"!

Actinomycin D is a cyclic polypeptide-containing antibiotic that binds to DNA and blocks transcription. It binds to pre-melted double-stranded DNA in transcription bubbles and once bound is slow to dissociate. DNA in transcriptionally hyperactive cancer cells efficiently and rapidly bind actinomycin D at low...

Actinomycin D is a nonfluorescent GC-selective intercalator. Similar to 7-AAD, actinomycin D has also been used for chromosome banding studies.Orange red solid soluble in DMSO at 50 mg/mL,Store at 4°C,C62H86N12O16,MW: 1255.43,

Antibiotic, Antitumor compound, Cytotoxic, Apoptosis inducer, RNA synthesis inhibitor, DNA intercalating agent, Mcl-1 expression inhibitor, p53 pathway activator. Isolated from Streptomyces parvulus.

Salmon Pink Crystal Powder. Actinomycin D is an antibiotic that is from several Steptomyces species. It is an intercalating transcription inhibitor.

Suitable for use in nucleic acid inhibition. Actinomycin D inhibits the proliferation of cells in a cell-cycle nonspecific way by forming a stable complex with DNA (via deoxyguanosine residues), thus inhibiting DNA-primed RNA synthesis. It is used in cell culture as a selection agent. Antibiotic. Antitumor compound....

Red to orange solid. Soluble in acetone or methanol. Biochemical/physiological actions: An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Potent antitumor agent. For cell...