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Item number: TGM-T5385-100mg

Description: Radiprodil (RGH-896) (RGH-896) is an orally active and selective NMDA NR2B receptors antagonist. It was a potential treatment of neuropathic pain associated with diabetic peripheral neuropathy (DPNP). Target: NMDAR, iGluR. Smiles: Fc1ccc(CC2CCN(CC2)C(=O)C(=O)Nc2ccc3[nH]c(=O)oc3c2)cc1. References: Labas...

Keywords:	RGH-896
Application:	NR2B subunit-containing NMDA receptor antagonist
CAS	496054-87-6
MW:	397.4 D

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Radiprodil

Item number: Cay29712-10

Radiprodil is an antagonist of NR2B subunit-containing NMDA receptors (IC50 = 8 nM). It is selective for NR2B subunit-containing NMDA receptors over NR1 and NR2A subunit-containing NMDA receptors at 15 µM. Radiprodil (10 nM) reduces amyloid beta (1-42) (Abeta42) and Abeta40-induced decreases in dendritic spine...

Keywords:	N-(2,3-dihydro-2-oxo-6-benzoxazolyl)-4-[(4-fluorophenyl)methyl]-alpha-oxo-1-piperidineacetamide
Application:	NR2B subunit-containing NMDA receptor antagonist
CAS	496054-87-6
MW:	397.4 D

From 149.00€ *

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