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CAY10684
Item number: Cay15966-1
Prostaglandin E2 (PGE2, Cay-14010) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a G protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. CAY10684 is a lactam that acts as a potent EP4 agonist,...
| Keywords: | (2R)-2-[(1E)-3-(4'-chloro-2'-methyl[1,1'-biphenyl]-3-yl)-3-hydroxy-1-propen-1-yl]-5-oxo-1-pyrrolidineheptanoic acid |
| Application: | EP4 agonist |
| CAS | 493035-81-7 |
| MW: | 470 D |
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EP4 receptor agonist 2
Item number: TGM-T84402-10mg
Description: EP4 receptor agonist 2 (compound 31) is a potent EP4 receptor agonist, demonstrating an EC50 value of 0.8 nM and K_i values of >100,000, 38,000, and 3.1 nM for the EP2, EP3, and EP4 receptors, respectively [1]. Target: Others. Smiles: Cc1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O
| Application: | EP4 agonist |
| CAS | 493035-81-7 |
| MW: | 470.01 D |
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