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Item number: TGM-T15481-100mg

Description: HI-TOPK-032 is an effective and specific inhibitor of TOPK. Target: TOPK. Smiles: O=C(Nc1ccn2c(c1)c(C#N)c1nc3ccccc3nc21)c1cccs1. References: Kim DJ, et al. Novel TOPK inhibitor HI-TOPK-032 effectively suppresses colon cancer growth. Cancer Res. 2012 Jun 15,72(12):3060-8.

Application:	PBK inhibitor
CAS	487020-03-1
MW:	369.4 D

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HI TOPK 032

Item number: Cay19815-5

HI TOPK 032 is an inhibitor of lymphokine-activated killer T cell-originated protein kinase (TOPK), blocking phosphorylation of the substrate histone H2AX with an IC50 value of ~2 µM and providing complete inhibition at 5 µM. It also inhibits checkpoint kinase 1 (Chk1, IC50 = 9.6 µM). In addition, HI TOPK 032...

Keywords:	N-(12-cyanoindolizino[2,3-b]quinoxalin-2-yl)-2-thiophenecarboxamide
Application:	PBK inhibitor
CAS	487020-03-1
MW:	369.4 D

From 47.00€ *

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