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Item number: TGM-TN1519-10mg

Description: (S)-Coclaurine (Coclaurine) is an antagonist of nAChR isolated from Sarcopetalum harveyanum. Target: AChR. Smiles: COc(cc(CCNC1Cc(cc2)ccc2O)c1c1)c1O. References: Kimura I, et al. Inotropic effects of (+/-)-higenamine and its chemically related components, (+)-R-coclaurine and (+)-S-reticuline, contained...

Keywords:	Coclaurine
CAS	486-39-5
MW:	285.34 D

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Coclaurine

Item number: Cay35716-1

Coclaurine is a benzylisoquinoline alkaloid that has been found in T. quinquenervia and has nicotinic acetylcholine receptor (nAChR) inhibitory and insecticidal activities. It inhibits ACh-induced currents in Xenopus oocytes expressing human alpha4beta2 or alpha4beta4 subunit-containing nAChRs (IC50s = 49 and 18 µM,...

Keywords:	(-)-Coclaurine, (S)-Coclaurine, (1S)-1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-7-isoquinolinol
Application:	Benzylisoquinoline alkaloid
CAS	486-39-5
MW:	285.3 D

From 153.00€ *

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