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Bicuculline
Item number: TGM-T2850-1mL
Description: Bicuculline ((+)-Bicuculline) is a light-sensitive competitive antagonist of GABAA receptors, originally identified in 1932 from plant alkaloid extracts, and isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and various Corydalis species. Target: GABA Receptor. Smiles:...
| Keywords: | d-Bicuculline, (+)-Bicuculline |
| CAS | 485-49-4 |
| MW: | 367.35 D |
From 40.00€
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Bicuculline
Item number: Cay11727-50
Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influence on target neurons. These receptors are the major targets for benzodiazepines and related anxiolytic drugs. Bicuculline is a competitive GABAA receptor...
| Keywords: | NSC 32192, 6-[(5S)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-(6R)-furo[3,4-e]-1,3-benzodioxol-8(6H)-one |
| Application: | GABAA receptor antagonist |
| CAS | 485-49-4 |
| MW: | 367.4 D |
From 61.00€
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(+)-Bicuculline
Item number: CDX-B0239-M025
Off-white to yellow powder. Soluble in chloroform. GABAA receptor antagonist.
| Keywords: | (6R)-6-[(5S)-6-Methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]furo[3,4-e][1,3]benzodioxol-8(6H)-one |
| Application: | GABAA receptor antagonist |
| CAS | 485-49-4 |
| MW: | 367,35 D |
From 87.00€
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(+)-Bicuculline
Item number: LKT-B3211.100
A light-sensitive competitive antagonist of GABAA receptors, extracted from plant alkaloid extracts. Also blocks Ca2+-activated potassium channels. Specific rotation +130 (20 D, chloroform c=2)
| CAS | 485-49-4 |
| MW: | 367.35 D |
From 113.00€
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