Description: N-Nornuciferine, an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 µM, Ki: 2.34 µM). Target: P450. Smiles: COc1cc2CCN[C@@H]3Cc4ccccc4-c(c1OC)c23. References: Ye LH, et al. Identification and characterization of potent CYP2D6 inhibitors in lotus leaves. J Ethnopharmacol. 2014...

N-Nornuciferine is an alkaloid that has been found in A. grandifolia and has cholinesterase inhibitory activity. It is an inhibitor of butyrylcholinesterase (BChE, IC50 = 5.6 µM for the mouse enzyme).Formal Name: 5,6,6aR,7-tetrahydro-1,2-dimethoxy-4H-dibenzo[de,g]quinoline. CAS Number: 4846-19-9. Synonyms:...