Description: Osthole (Osthol), a potential inhibitor of histamine H1 receptor, has been shown to stimulate osteoblast proliferation and differentiation. Target: HBV, Apoptosis, Parasite, Histamine Receptor. Smiles: COC1=C(C\C=C(/C)C)C2=C(C=CC(=O)O2)C=C1. References: Ko FN, et al. Thromb Haemost, 1989, 62(3),...

Osthole is a coumarin that has been found in C. monnieri and has diverse biological activities. It decreases secretion of hepatitis B surface antigen (HBsAg) from Huh7 cells transfected with hepatitis B virus (HBV) DNA by 70% when used at a concentration of 20 µg/ml. Osthole induces bone morphogenetic protein 2...

A coumarin isolated from Cnidium monnieri (L.) Cusson It is an antiplatelet agent that inhibits phosphoinositide breakdown. It also prevents anti-Fas antibody-induced hepatitis in mice.

White to off-white powder. Soluble in DMSO, DMF, ethanol (all 20mg/ml) or methanol (10mg/ml). Chemical. CAS: 484-12-8. Formula: C15H16O3. MW: 244.29. Synthetic. Osthole is a natural coumarin that was first isolated from several medicinal plants, including C. monnieri and A. pubescens. Osthole exhibits...