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RG108
RG108

Item number: TGM-T2038-100mg

Description: RG108 (N-Phthalyl-L-tryptophan) is a DNA methyltransferase inhibitor with an IC50 of 115 nM. Target: DNA Methyltransferase. Smiles: [C@H](CC=1C=2C(NC1)=CC=CC2)(C(O)=O)N3C(=O)C=4C(C3=O)=CC=CC4. References: Brueckner B, et al, Cancer Res, 2005, 65(14), 6305-6311.
Keywords: N-Phthalyl-L-tryptophan
Application: DNA methyltransferase inhibitor
CAS 48208-26-0
MW: 334.33 D
From 40.00€ *
Review
RG108
RG108

Item number: Cay13302-10

DNA methylation regulates gene expression in normal and malignant cells. RG108 is a non-nucleoside DNA methyltransferase inhibitor (IC50 = 115 nM in vitro). It significantly reduces the methylation of genomic DNA in cells at 10 µM without detectable toxicity, distinguishing it from nucleoside-based inhibitors like...
Keywords: N-Phthalyl-L-Tryptophan, alpha-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-(alphaS)-1H-indole-3-propanoic acid
Application: DNA methyltransferase inhibitor
CAS 48208-26-0
MW: 334.3 D
From 85.00€ *
Review
RG-108
RG-108

Item number: LKT-R2400.10

DNMT inhibitor.
Application: DNMT inhibitor
CAS 48208-26-0
MW: 334.33 D
From 125.00€ *
Review