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Indirubin
Item number: LKT-I5212.5
Indirubin is a bisindole isomer of indigo, naturally sourced from Indigo naturalis. Indirubin exhibits anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic activities. In vivo, indirubin decreases levels of IgE and production of inflammatory cytokines, decreasing overall inflammation as well as skin...
| Application: | CDK inhibitor |
| CAS | 479-41-4 |
| MW: | 262.26 D |
From 109.00€
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Indirubin
Item number: TGM-T6169-100mg
Description: Indirubin (Couroupitine B) is a potent inhibitor of cyclin-dependent kinases and GSK-3beta, with IC50 values of approximately 5 µM and 0.6 µM, respectively. Target: Raf, GSK-3, CDK, Apoptosis. Smiles: O=C1Nc2ccccc2C1=C1Nc2ccccc2C1=O. References: Hoessel R, et al. Nat Cell Biol, 1999, 1(1), 60-67.
| Keywords: | Couroupitine B, NSC 105327, Indigopurpurin, Indigo red |
| Application: | GSK-3 inhibitor, CDK1/5 inhibitor |
| CAS | 479-41-4 |
| MW: | 262.26 D |
From 45.00€
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Indirubin
Item number: Cay14155-5
Indirubin is a natural product originally extracted from roots and leaves of the Indigo plant (I. tinctoria) used in traditional Chinese medicine for anti-inflammatory, anti-tumor, and neuroprotective effects. Indirubin inhibits glycogen synthase kinase-3 (IC50 = 2.5 µM) and cyclin-dependent kinases 1 and 5 (IC50 =...
| Keywords: | C.I. 73200, Couroupitine B, Indigopurpurin, NSC 105327, 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one |
| Application: | GSK-3 inhibitor, CDK1/5 inhibitor |
| CAS | 479-41-4 |
| MW: | 262.3 D |
From 83.00€
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