2 products were found matching "477600-75-2"!

No results were found for the filter!
Tofacitinib, Free Base (Tasocitinib, CP-690550, Xeljanz, CAS 477600-75-2), >99%
Tofacitinib, Free Base (Tasocitinib, CP-690550, Xeljanz,...

Item number: LC-T-1377_1g

Soluble in DMSO at 100 mg/mL, soluble in ethanol at 100 mg/mL, very poorly soluble in water, maximum solubility in plain water is estimated to be about 10-20 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
Application: JAK3 inhibitor
CAS 477600-75-2
MW: 312,37 D
From 94.00€ *
Review
COVID-19 Research
Tofacitinib
Tofacitinib

Item number: AG-CR1-3625-M005

Off-white to pale yellow solid. Soluble in DMSO or ethanol. Potent cell permeable JAK3 inhibitor (IC50 = 1nM). Shows also JAK-1 inhibitory activity, Immunosuppressive and anti-inflammatory agent, Inhibits signaling through heterodimeric receptors associated with JAK3, JAK1, or both of them, with functional...
Keywords: CP-690550, Xeljanz, Tasocitinib
Application: Cell-permeable JAK3 inhibitor
CAS 477600-75-2
MW: 312,4 D
From 77.00€ *
Review