2 products were found matching "477575-56-7"!
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PHA-665752
Item number: TGM-T6128-100mg
Description: PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs. Target: VEGFR, FGFR, Autophagy, Bcr-Abl, c-Met/HGFR, Apoptosis. Smiles:...
| Keywords: | PHA 665752, PHA665752 |
| Application: | ATP-competitive, active-site c-Met kinase inhibitor |
| CAS | 477575-56-7 |
| MW: | 641.61 D |
From 60.00€
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PHA-665752
Item number: Cay14703-1
The c-Met receptor tyrosine kinase and its ligand, hepatocyte growth factor, have been implicated in the development and progression of several human cancers. PHA-665752 is an ATP-competitive, active-site inhibitor of the catalytic activity of c-Met kinase (Ki = 4 nM, IC50 = 9 nM). It exhibits >50-fold selectivity...
| Keywords: | (3Z)-5-[[(2,6-dichlorophenyl)methyl]sulfonyl]-3-[[3,5-dimethyl-4-[[(2R)-2-(1-pyrrolidinylmethyl)-1-pyrrolidinyl]carbonyl]-... |
| Application: | ATP-competitive, active-site c-Met kinase inhibitor |
| CAS | 477575-56-7 |
| MW: | 641.6 D |
From 67.00€
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