Description: Colchicoside (3-Demethylcolchicine glucoside) is extracted from Gloriosa superba and shows efficacy in a murine model of pancreatic adenocarcinoma. Target: Others. Smiles: COC1=C(OC)C2=C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)C=C1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O. References: Capistrano I R, et...

Colchicoside is a glycoside form of 3-demethylcolchicine that has been found in G. superba. Unlike cholchicine and 3-demethylcolchicine, colchicoside does not displace [3H]-colchicine from rat brain tubulin in vitro when used at a concentration of 25 µM. Colchicoside (1 and 10 µM) increases levels of the cytochrome...