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VO-Ohpic trihydrate
Item number: TGM-T7012-100mg
Description: VO-Ohpic trihydrate (VO-Ohpic) is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM. Target: PTEN, Autophagy. Smiles: O=C1O[V+](=O)(Oc2c1nccc2)OC(=O)c1ncccc1O.O.O.O.O.[H-]. References: Rosivatz E, et al. ACS Chem Biol. 2006,1(12):780-90.
| Keywords: | VO-Ohpic |
| Application: | PTEN inhibitor |
| CAS | 476310-60-8 |
| MW: | 415.2 D |
From 52.00€
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VO-OHpic (hydrate)
Item number: Cay10009965-1
VO-OHpic is a specific inhibitor of phosphatase and tensin homolog (PTEN, IC50 = 35 nM in vitro). Through this action, it increases cellular phosphatidylinositol 3,4,5-trisphosphate (PIP3) levels, phosphorylation of Akt, and glucose uptake in adipocytes. In mice, VO-OHpic (10 µg/kg, i.p.) decreases left ventricular...
| Keywords: | (OC-6-45)-aqua(3-hydroxy-2-pyridinecarboxylato-kappaN1,kappaO2)[3-(hydroxy-kappaO)-2-pyridinecarboxylato(2-)-kappaO2]oxo-v... |
| Application: | PTEN inhibitor |
| CAS | 476310-60-8 |
| MW: | 415.2 D |
From 44.00€
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