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Item number: TGM-T5S0055-1mL

Description: 1. Chelidonine (Stylophorin) isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways. 2. Chelidonine is a promising model compound for overcoming MDR and for enhancing cytotoxicity of chemotherapeutics,...

Keywords:	Stylophorin, Khelidonin, Helidonine
CAS	476-32-4
MW:	353.37 D

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Chelidonine

Item number: Cay25097-1

Chelidonine is a benzophenanthridine alkaloid that has been isolated from C. majus. It induces Bcl-2- and caspase-dependent apoptosis in HepG2 human liver carcinoma cells with an LC50 value of 12 µM and in Jurkat human T cells when used at a concentration of 1 µM. Chelidonine also downregulates hTERT expression in...

Keywords:	5bR,6S,7,12bS,13,14-hexahydro-13-methyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol
Application:	Apoptosis inducer
CAS	476-32-4
MW:	353.4 D

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