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Monomethyl auristatin E
Monomethyl auristatin E

Item number: TGM-T6897-10mg

Description: Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody-drug conjugates (ADCs) activity. Target: Microtubule Associated, Apoptosis, ADC Cytotoxin. Smiles:...
Keywords: Vedotin, MMAE
Application: Targets tubulin beta (TUBB)
CAS 474645-27-7
MW: 717.98 D
From 42.00€ *
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Monomethyl Auristatin E
Monomethyl Auristatin E

Item number: Cay16267-5

Dolastatin 10 is a natural antimitotic and antineoplastic agent that binds to tubulin and inhibits tubulin polymerization. Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is commonly conjugated with monoclonal...
Keywords: Brentuximab vedotin, MMAE,...
Application: Antineoplastic agent, Antimitotic
CAS 474645-27-7
MW: 718 D
From 111.00€ *
Review