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MK-0752
MK-0752

Item number: TGM-T2625-100mg

Description: MK-0752, a gamma-secretase inhibitor, reduces Abeta40 production(IC50=5 nM). Target: Gamma-secretase, Beta Amyloid. Smiles: OC(=O)CC[C@H]1CC[C@@](CC1)(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1. References: Cook JJ, et al. J Neurosci, 2010, 30(19), 6743-6750.
Application: gamma-secretase inhibitor
CAS 471905-41-6
MW: 442.9 D
From 52.00€ *
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MK-0752
MK-0752

Item number: Cay16706-1

gamma-Secretase is a protease complex that cleaves single-pass transmembrane proteins, such as Notch receptors and beta-amyloid precursor protein (APP), within the transmembrane domain. MK-0752 is a potent, reversible inhibitor of gamma-secretase, reducing the cleavage of APP to Abeta40 in human neuroblastoma...
Keywords: cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)-cyclohexanepropanoic acid
Application: gamma-secretase inhibitor
CAS 471905-41-6
MW: 442.9 D
From 94.00€ *
Review
MK-0752
MK-0752

Item number: LKT-M4200.1

gamma-Secretase inhibitor.
Application: gamma-Secretase inhibitor
CAS 471905-41-6
MW: 442.9 D
From 109.00€ *
Review