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beta-Lapachone
Item number: TGM-T6407-100mg
Description: beta-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase. Target: Autophagy, Apoptosis, IDO, Topoisomerase. Smiles: CC1(C)CCC2=C(O1)c1ccccc1C(=O)C2=O. References: Li CJ, et al. J Biol Chem. 1993, 268(30), 22463-22468.
| Keywords: | Beta-Lapachone, SL-11001, NSC-26326, ARQ-501 |
| Application: | Topoisomerase I and transglutaminase inhibitor |
| CAS | 4707-32-8 |
| MW: | 242.27 D |
From 42.00€
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beta-Lapachone
Item number: Cay15021-5
beta-Lapachone is a natural quinone with diverse anti-cancer and anti-inflammatory effects. It inhibits topoisomerase I at 25 µM and transglutaminase (IC50 = 5 µM). In cancer cells which overexpress NAD(P)H:quinone oxidoreductase, beta-lapachone is reduced to beta-lapachone hydroquinone, which generates reactive...
| Keywords: | ARQ 501, NSC 26326, NSC 629749, SL 11001, 3,4-dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione |
| Application: | Topoisomerase I and transglutaminase inhibitor |
| CAS | 4707-32-8 |
| MW: | 242.3 D |
From 99.00€
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