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Item number: TGM-T4S0537-10mg

Description: Neoline is an active ingredient of A. venetum root (PA) that ameliorates oxaliplatin-induced peripheral neuropathy in mice.Neoline inhibits Nav1.7 voltage-gated sodium channel currents (VGSC). It can be used as a labeling compound to determine the quality of PA products used in the study of neuropathic...

Keywords:	Bullatine B
Application:	Diterpene alkaloid
CAS	466-26-2
MW:	437.57 D

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Bullatine B

Item number: Cay36170-1

Bullatine B is a diterpene alkaloid that has been found in Aconitum and has diverse biological activities. It inhibits voltage-gated sodium channel 1.7 (Nav1.7) in HEK293 cells expressing the human channel (IC50 = 25.8 nM) and scavenges DPPH (Cay-14805) radicals by 65.3% at 1 mM. Bullatine B (10 mg/kg) increases the...

Keywords:	Neoline, 20-ethyl-6,16-dimethoxy-4-(methoxymethyl)-(1alpha,6alpha,14alpha,16beta)-aconitane-1,8,14-triol
Application:	Diterpene alkaloid
CAS	466-26-2
MW:	437.6 D

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