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Eact
Item number: TGM-T15192-100mg
Description: Eact is a selective and potent TMEM16A activator that directly activates the TRPV1 channels in sensory nociceptors, thereby producing itch, acute nociception, and thermal hypersensitivity (brackets). Target: Chloride channel. Smiles: COCCN(C(=O)c1cc(OC)c(OC)c(OC)c1)c1nc(cs1)-c1ccccc1. References: Liu S,...
| Application: | ANO1 activator |
| CAS | 461000-66-8 |
| MW: | 428.5 D |
From 34.00€
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Eact
Item number: Cay29791-1
Eact is an activator of the calcium-activated chloride channel anoctamin 1 (ANO1). It increases chloride currents in FRT cells expressing human ANO1 (EC50 = 3 µM). It is selective for ANO1 over cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels and epithelial sodium channels (ENaCs) in FRT...
| Keywords: | 3,4,5-trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)-benzamide |
| Application: | ANO1 activator |
| CAS | 461000-66-8 |
| MW: | 428.5 D |
From 52.00€
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