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Item number: TGM-T15446-100mg

Description: GT 949 is a selective excitatory positive allosteric modulator of amino acid transporter-2 (EAAT2) with an EC50 of 0.26 nM. Target: transporter. Smiles: COc1ccc2[nH]c(=O)c(cc2c1)C(N1CCN(CC1)C1CCCCC1)c1nnnn1CCc1ccccc1. References: Kortagere S, et al. Identification of Novel Allosteric Modulators of...

Application:	EEAT2 positive allosteric modulator
CAS	460330-27-2
MW:	527.66 D

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GT 949

Item number: Cay34552-5

GT 949 is a positive allosteric modulator of excitatory amino acid transporter 2 (EAAT2, EC50 = 0.26 nM for stimulating glutamate uptake by COS-7 cells expressing EAAT2). It is selective for EEAT2 over the serotonin (5-HT) transporter (SERT), the norepinephrine transporter (NET), and the dopamine transporter (DAT,...

Keywords:	3-[(4-cyclohexyl-1-piperazinyl)[1-(2-phenylethyl)-1H-tetrazol-5-yl]methyl]-6-methoxy-2(1H)-quinolinone
Application:	EEAT2 positive allosteric modulator
CAS	460330-27-2
MW:	527.7 D

128.00€ *

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