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Item number: Cay33221-1

Pexacerfont is an antagonist of corticotropin-releasing factor receptor 1 (CRF1, IC50 = 6.1 nM for the human receptor). It is selective for CRF1 in IMR-32 cells (mean IC50 = 10.6 nM) over CFR2beta receptors endogenously expressed in pig choroid plexus membranes (IC50 = >1,000 nM) in radioligand binding assays and...

Keywords:	BMS 562086, DPC-A69448,...
Application:	CRF1 antagonist
CAS	459856-18-9
MW:	340.4 D

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