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SW033291
SW033291

Item number: TGM-T2121-100mg

Description: SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues. Target: Dehydrogenase. Smiles: CCCCS(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1. References: Zhang Y, et al. Science. 2015, 348(6240), aaa2340.
CAS 459147-39-8
MW: 412.59 D
From 34.00€ *
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SW033291
SW033291

Item number: Cay18040-5

The enzyme 15-hydroxy prostaglandin dehydrogenase (15-PGDH) initiates the catabolism of PGs and related eicosanoids. SW033291 is a potent inhibitor of 15-PGDH (Ki = ~0.1 nM) that has activity in vivo. It rapidly increases the levels of PGE2 in bone marrow and other tissues in mice after intraperitoneal injection....
Keywords: 2-(butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridine-3-amine
Application: 15-PGDH inhibitor
CAS 459147-39-8
MW: 412.6 D
From 62.00€ *
Review