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Item number: Cay21904-1

Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 µM for murine and human Piezo1-transfected HEK293T cells, respectively). It is selective for Piezo1 as it elicits Ca2+ flux in Piezo1- but not Piezo2-transfected HEK293T cells. Yoda1 slows the inactivation phase of murine Piezo1 transient currents and...

Keywords:	2-[5-[[(2,6-dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]-pyrazine
Application:	Piezo1 agonist
CAS	448947-81-7
MW:	355.3 D

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