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Item number: TGM-T3192-100mg

Description: NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 µM. Target: HER, Autophagy, Potassium Channel. Smiles: Oc1ccc(cc1NC(=O)Nc1cc(ccc1O)C(F)(F)F)C(F)(F)F. References: Casis O, et al. Mol Pharmacol. 2006 Feb,69(2):658-65.

Application:	KCNH2 activator
CAS	448895-37-2
MW:	380.24 D

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NS 1643

Item number: Cay20343-10

NS 1643 is an activator of the human ether-a-go-go related gene (ERG1, KCNH2, hERG) KV11.1 channel (EC50 = 10.5 µM). It also activates the KV11.2 (ERG2, KCNH6) channel, but evokes a distinctly different response from that of KV11.1. NS 1643 is commonly used in cells or isolated tissues.Formal Name:...

Keywords:	N,N'-bis[2-hydroxy-5-(trifluoromethyl)phenyl]-urea
Application:	KCNH2 activator
CAS	448895-37-2
MW:	380.2 D

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