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Item number: TGM-T4352-100mg

Description: SB756050 is a specific TGR5 agonist. Target: GPCR19. Smiles: COc1ccc(cc1OC)S(=O)(=O)N1CCCN(CC1)S(=O)(=O)c1ccc(OC)c(OC)c1. References: Hodge RJ, et al. Safety, Pharmacokinetics, and Pharmacodynamic Effects of a Selective TGR5 Agonist, SB-756050, in Type 2 Diabetes. Clin Pharmacol Drug Dev. 2013...

Keywords:	SB-756050, SB 756050
Application:	TGR5 agonist
CAS	447410-57-3
MW:	500.59 D

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SB-756050

Item number: Cay27998-10

SB-756050 is an agonist of the bile acid G protein-coupled receptor TGR5 (EC50 = 1.3 µM for the human receptor). It is selective for TGR5 over the farnesoid X receptor (FXR) and a panel of other receptors, channels, and transporters. SB-756050 (10-100 mg/kg) decreases fasting glucose levels and increases glucose...

Keywords:	1,4-bis[(3,4-dimethoxyphenyl)sulfonyl]hexahydro-1H-1,4-diazepine
Application:	TGR5 agonist
CAS	447410-57-3
MW:	500.6 D

From 44.00€ *

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