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CP671305
Item number: TGM-T4695-100mg
Description: CP671305 is an orally active, potent and selective inhibitor of phosphodiesterase-4-D. Target: PDE. Smiles: C[C@@H](Oc1ccc(CNC(=O)c2cccnc2Oc2ccc3OCOc3c2)c(F)c1)C(O)=O. References: Kalgutkar AS, et al. Role of transporters in the disposition of the selective phosphodiesterase-4 inhibitor...
| Application: | PDE4D inhibitor |
| CAS | 445295-04-5 |
| MW: | 454.4 D |
From 32.00€
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CP 671,305
Item number: Cay26743-1
CP 671,305 is a potent inhibitor of phosphodiesterase 4D (PDE4D, IC50 = 3 nM). It is selective for PDE4D over PDE4A, -B, and -C (IC50s = 310, 287, and 3,858 nM, respectively), as well as over PDE1-3 and 5 (IC50s = >5,000 nM for all). CP 671,305 inhibits release of leukotriene E4 (LTE4, Cay-20410) from eosinophils...
| Keywords: | (2R)-2-[4-[[[[2-(1,3-benzodioxol-5-yloxy)-3-pyridinyl]carbonyl]amino]methyl]-3-fluorophenoxy]-propanoic acid |
| Application: | PDE4D inhibitor |
| CAS | 445295-04-5 |
| MW: | 454.4 D |
From 60.00€
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