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CDDO-Im
Item number: TGM-TQ0120-100mg
Description: CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARalpha/PPARgamma). Target: PPAR, Others, Ferroptosis, Nrf2. Smiles: [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)[C@]2([H])C(=O)C=C2[C@@]1(C)CC[C@@]1([H])C(C)(C)C(=O)C(=C[C@]21C)C#N)C(=O)n1ccnc1. References: Place AE, et al. The novel...
| Keywords: | CDDO-Imidazolide, RTA-403, TP-235 |
| Application: | Nrf2 signaling activator |
| CAS | 443104-02-7 |
| MW: | 541.72 D |
From 34.00€
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CDDO-Im
Item number: Cay31763-1
CDDO-Im is a synthetic triterpenoid and an activator of Nrf2 signaling. It binds to Keap1, inhibiting the degradation of Nrf2 and leading to increased Nrf2 protein levels. CDDO-Im (100 nM) increases the expression of Nrf2 target genes and activates heme oxygenase-1 (HO-1) in a reporter assay using CV-1 cells. It...
| Keywords: | CDDO-Imidazolide, RTA 403, 1-(2-cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole |
| Application: | Nrf2 signaling activator |
| CAS | 443104-02-7 |
| MW: | 541.7 D |
From 100.00€
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