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Item number: Cay29038-1

CK-666 is an inhibitor of the actin-related protein 2/3 (Arp2/3) complex (IC50s = 4, 17, and 5 µM for the human, bovine, and S. pombe complexes, respectively, in an actin polymerization assay). It binds at the Arp2/3 interface, stabilizing the inactive conformation of the complex. CK-666 (40 µM) inhibits actin comet...

Keywords:	2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]-benzamide
Application:	Arp2/3 complex inhibitor
CAS	442633-00-3
MW:	296.3 D

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