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CeMMEC1
Item number: TGM-T4345-100mg
Description: CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 µM). Target: DNA/RNA Synthesis, Epigenetic Reader Domain, Carboxypeptidase. Smiles: Cn1cc(C(=O)Nc2ccc3OCCOc3c2)c2ccccc2c1=O. References: Sdelci S,etal. Mapping the chemical chromatin reactivation landscape identifies...
| Keywords: | CeMMEC1 HCl |
| Application: | TAF1 bromodomain inhibitor |
| CAS | 440662-09-9 |
| MW: | 336.34 D |
From 31.00€
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CeMMEC1
Item number: Cay19956-1
CeMMEC1 is an N-methylisoquinolinone that inhibits the second bromodomain of TAF1 (Kd = 1.8 µM, IC50 = 0.9 µM). It does not bind to either the first or second bromodomain of BRD4. This compound synergizes with (+)-JQ1 (Cay-11187) to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.Formal Name:...
| Keywords: | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-2-methyl-1-oxo-4-isoquinolinecarboxamide |
| Application: | TAF1 bromodomain inhibitor |
| CAS | 440662-09-9 |
| MW: | 336.3 D |
From 44.00€
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