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Trifluoperazine (hydrochloride)
Item number: Cay15068-1
Trifluoperazine (TFP) is a phenothiazine compound with anti-adrenergic and anti-dopaminergic actions typical of antipsychotic agents. It antagonizes adrenergic receptors, with selectivity for alpha1 over the alpha2 subtypes (Kis = 24, 653, 163, and 391 nM for alpha1A, alpha2A, alpha2B, and alpha2C, respectively)....
| Keywords: | SKF 5019, TFP, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine, dihydrochloride |
| Application: | Dopamine receptor D2 antagonist |
| CAS | 440-17-5 |
| MW: | 480.4 D |
From 43.00€
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Trifluoperazine HCl
Item number: LKT-T7033.5
A phenothiazine class calmodulin antagonist which is known for its inhibition of DNA synthesis and cell proliferation activities. It is shown to stimulate Egr-1 gene experession by modulating Ras/MEK/ERK and activation of the E1K-1 pathway in human fibrosarcoma HT1080 cells. Trifluoperazine also induces apoptosis in...
| Keywords: | Trifluoperazine hydrochloride |
| Application: | Calmodulin antagonist |
| CAS | 440-17-5 |
| MW: | 480,43 D |
From 117.00€
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