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(Z)-SMI-4a
(Z)-SMI-4a

Item number: TGM-T3058-100mg

Description: (Z)-SMI-4a (TCS PIM-1 4a) is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM. Target: Pim. Smiles: FC(F)(F)C1=CC=CC(\C=C2\SC(=O)NC2=O)=C1. References: Beharry Z, et al. Mol Cancer Ther, 2009, 8(6), 1473-1483.
Keywords: SMI-4a, TCS PIM-1 4a
Application: Pim-1/Pim-2 kinase inhibitor
CAS 438190-29-5
MW: 273.23 D
From 46.00€ *
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SMI-4a
SMI-4a

Item number: Cay11029-5

The serine/threonine Pim kinases have been suggested to promote the activity of the rapamycin-sensitive mammalian target of rapamycin (mTORC1), which regulates cell growth and survival. Pim kinases are overexpressed in solid cancers and hematologic malignancies, and as such have become targets of small molecule...
Keywords: 5Z-[[3-(trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione
Application: Pim-1/Pim-2 kinase inhibitor
CAS 438190-29-5
MW: 273.2 D
From 61.00€ *
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SMI-4a
SMI-4a

Item number: LKT-S4932.10

Thiazolidine, Pim kinase inhibitor.
Application: Thiazolidine, Pim kinase inhibitor
CAS 438190-29-5
MW: 273.23 D
From 117.00€ *
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