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Kobe0065
Kobe0065

Item number: TGM-T1876-100mg

Description: Kobe0065 is a novel and effective small-molecule compound that inhibits the Ras-Raf interaction by structure-based drug design (SBDD), it displays potent activity, competitively inhibiting the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 µM. Target: Raf, Apoptosis, Ras. Smiles:...
Application: Ras inhibitor
CAS 436133-68-5
MW: 449.79 D
From 39.00€ *
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Kobe 0065
Kobe 0065

Item number: Cay16261-5

The Ras family of small GTPases (H-Ras, K-Ras, and N-Ras) function as molecular switches, cycling between a GTP-bound active state and a GDP-bound inactive state, to turn on downstream Raf protein kinases. This initiates complex signaling pathways involved in cell growth, differentiation, and apoptosis. Mutations...
Keywords: N-(3-chloro-4-methylphenyl)-2-[2,6-dinitro-4-(trifluoromethyl)phenyl]-hydrazinecarbothioamide
Application: Ras inhibitor
CAS 436133-68-5
MW: 449.8 D
From 50.00€ *
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Kobe 0065
Kobe 0065

Item number: LKT-K5604.25

Ras inhibitor.
Application: Ras inhibitor
CAS 436133-68-5
MW: 449.79 D
From 167.00€ *
Review