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Teglarinad chloride
Teglarinad chloride

Item number: TGM-T26254-1mg

Description: Teglarinad chloride (GMX-1777 chloride) is a potent inhibitor of NAMPT, the precursor of GMX1778.Teglarinad chloride has antitumor activity and acts by interfering with DNA repair and inhibiting angiogenesis. Target: NAMPT. Smiles: [Cl-].COCCOCCOCC...
Keywords: GMX 1777, GMX-1777 chloride, GMX1777 chloride, GMX 1777 chloride, EB1627, GMX1777, EB-1627, EB-1627 chloride, EB1627 chloride
Application: Targets nicotinamide phosphoribosyltransferase [EC:2.4.2.12] (NAMPT)
CAS 432037-57-5
MW: 672.6 D
205.00€ *
Review
GMX1777
GMX1777

Item number: Cay38798-1

GMX1777 is a prodrug form of the nicotinamide phosphoribosyltransferase (Nampt) inhibitor CHS-828 (Cay-11021). Intravenous administration of GMX1777 (75 and 150 mg/kg) reduces NAD+ levels in tumors, but not muscle tissue, in a DMS 273 lung cancer mouse xenograft model. GMX1777 (50 mg/kg per day), in combination with...
Keywords: EB1627, Teglarinad,...
Application: CHS-828 (Nampt inhibitor) prodrug form
CAS 432037-57-5
MW: 672.6 D
From 135.00€ *
Review