Nabumetone is a non-steroidal anti-inflammatory drug (NSAID) and a prodrug form of 6-methoxy naphthalene acetic acid (Cay-70620). Nabumetone (5-45 mg/kg) reduces carrageenan-induced edema in rats, as well as UV-induced erythema in guinea pigs (ED50 = 11 mg/kg). It reduces phenyl-p-quinone-induced writhing in mice...

A non steroidal anti-inflammatory drug used to reduce inflammation and pain associated with rheumatoid arthritis and osteoarthritis. Nabumetone works by inhibiting cyclooxygenase, an enzyme responsible for making prostaglandins which are mediators of inflammation. It also has chemopreventive effect on chemically...