3 products were found matching "425386-60-3"!
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Semagacestat
Item number: TGM-T6125-100mg
Description: Semagacestat (LY450139) (LY450139) is a gamma-secretase blocker for Abeta42/Abeta40/Abeta38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM). Target: Beta Amyloid, Gamma-secretase. Smiles: CC(C)[C@H](O)C(=O)N[C@@H](C)C(=O)N[C@H]1c2ccccc2CCN(C)C1=O. References: Mitani Y, et...
| Keywords: | LY450139 |
| Application: | Dementia therapeutic agent, gamma-Secretase inhibitor |
| CAS | 425386-60-3 |
| MW: | 361.44 D |
From 34.00€
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Semagacestat
Item number: Cay16713-5
Semagacestat is a potent inhibitor of gamma-secretase that blocks the production of Abeta38, Abeta40, and Abeta42 with IC50 values of 12.0, 12.1, and 10.9 nM, respectively. It also blocks Notch signaling (IC50 = 14.1 nM). Semagacestat modulates gamma-secretase activity in vivo, altering Abeta levels in brain,...
| Keywords: | LY450139,... |
| Application: | gamma-secretase inhibitor |
| CAS | 425386-60-3 |
| MW: | 361.4 D |
From 52.00€
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LY-450139
Item number: LKT-L9701.1
GHS-R1a agonist, gamma-secretase inhibitor.
| Keywords: | Semagacestat |
| Application: | gamma-secretase inhibitor |
| CAS | 425386-60-3 |
| MW: | 361.44 D |
From 104.00€
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